Cardinals vs Browns odds, line, spread: 2021 NFL picks, week 6 predictions from proven computer model

When the Cleveland Browns (3-2) host the Arizona Cardinals (5-0) on Sunday afternoon, the outcome may have more to do with who is not on the field than who is. Arizona head coach Kliff Kingsbury tested positive for COVID-19 this week and will not be on the sidelines of the Cardinals. Meanwhile, running back Nick Chubb is unavailable for Cleveland with a calf injury.

Cleveland’s FirstEnergy Stadium kicks off at 4:05 p.m. ET. Cleveland is a three-point favorite in recent Browns vs. Cardinals from Caesars Sportsbook, while the total points scored is set at 48. Before entering the Cardinals vs. Browns, you’ll want to see the model’s NFL predictions on SportsLine.

The model, which simulates every NFL game 10,000 times, is up nearly $ 7,900 per 100 players on the NFL’s top picks since its inception over six years ago. He enjoyed a 24-14 sizzle over the NFL’s top-rated picks last season, grossing over $ 800. The model also enters week 6 of the 2021 season on an incredible 125-83 top-rated race. NFL pick which dates back to the 2017 season.

The model has also ranked in the top 10 on NFLPickWatch four of the past five years on NFL direct picks and has beaten over 94% of CBS Sports Football Pick’em players four times during that time. Whoever has followed him is WAY up.

Now the model has set its sights on Browns vs. Cardinals. You can go to SportsLine to see his choices. Here are several NFL betting lines for cardinals against browns:

  • Browns vs Cardinals Spread: Browns -3
  • Over-under Browns vs Cardinals: 48 points

Featured Game | Cleveland Browns vs. Arizona Cardinals

What you need to know about the Browns

Even without Chubb, the Browns should be able to move the ball to the ground against Arizona. The Cardinals will get a healthy dose of Kareem Hunt, who could cut an Arizona defense that allowed the NFL’s fifth rushing yards. Hunt should also be considered in the passing game, as Arizona has allowed opposing backers to catch 25 passes for 204 yards this season.

Cleveland had hoped to activate Jarvis Landry off the injured reserve for the game, but he will sit for another week. The Browns’ tight ends played a bigger role in the passing game, but Arizona gave the TE position the third-fewest receiving yards in 2021. Wide receiver Donovan Peoples-Jones stepped up last week with five catches for 70 yards in Week 5 for Cleveland, and could be in another big week against a Cardinals defense looking to stack the box against Hunt.

What you need to know about the Cardinals

The Cardinals started 5-0 for the first time since the 1974 season. DeAndre Hopkins’ 9-yard TD with 5:13 left gave Arizona a 17-7 lead on the way to victory. The Cardinals have stopped San Francisco four times in a fourth down conversion attempt. Kyler Murray had 239 yards and a touchdown.

Arizona head coach Kliff Kingsbury has tested positive for COVID-19 and will not be sidelined for Sunday’s game. Quarterbacks coach Cam Turner and defensive lineman Zach Allen have also tested positive and will miss the game against Cleveland. Defensive coordinator Vance Joseph and special teams coordinator Jeff Rodgers are expected to share head coaching duties. The status of Chandler Jones, who tested positive earlier this week, is uncertain.

How to make choices between Cardinals and Browns

The model has simulated Browns vs. Cardinals 10,000 times and the results are there. It looks at the total, and it also generated a point pick that hits in well over 50% of the simulations. You can only see the choice on SportsLine.

So who wins the Browns over the Cardinals? And which side of the gap reaches well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the computer model that crushed his NFL picks.


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